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Article

Estrogen receptor gene analysis in estrogen receptor-positive and receptor-negative primary breast cancer.

Journal of the National Cancer Institute - 15 Mar 1995

Roodi N, Bailey L R, Kao W Y, Verrier C S, Yee C J, Dupont W D, Parl F F

Abstract excerpt

BACKGROUND: In breast cancer patients, about two thirds of the tumors are estrogen receptor (ER)-positive and one third are ER-negative. The molecular mechanisms leading to the ER-negative phenotype are poorly understood. Nearly all ER-negative and about 40% of ER-positive cancers are resistant to endocrine therapy. PURPOSE: In this study, we examined the entire coding region of the ER gene in ER-positive and...

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PMID: 7861463
DOI: 10.1093/jnci/87.6.446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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