Article
Nuclear β-catenin localization and mutation of the CTNNB1 gene: a context-dependent association.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 2018
Kim Grace, Kurnit Katherine C, Djordjevic Bojana, Singh Charanjeet, Munsell Mark F, Wang Wei-Lien, Lazar Alexander J, Zhang Wei, Broaddus Russell
Abstract excerpt
Although the majority of low-grade, early-stage endometrial cancer patients have good survival with surgery alone, patients who recur tend to do poorly. Identification of patients at high risk of recurrence who would benefit from adjuvant treatment or more extensive surgical staging would help optimize individualized care of endometrial cancer patients. CTNNB1 (encodes β-catenin) mutations identify a subset of...
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