Article
Vascular smooth muscle nitric oxide synthase anomalies in Dahl/Rapp salt-sensitive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Apr 1998
Chen P Y, Gladish R D, Sanders P W
Abstract excerpt
Salt-sensitive hypertension in the Dahl/Rapp rat (S strain) is prevented by L-arginine. Based on the observations that dexamethasone prevented the antihypertensive effect of L-arginine in these animals and the suggestion that a locus in or near an inducible nitric oxide synthase (NOS) gene on chr...
Topics
- Animals
- Arginine
- DNA Primers
- Genotype
- Hypertension
- Molecular Sequence Data
- Muscle, Smooth, Vascular
- Mutation
- Nitric Oxide Synthase
- Nitric Oxide Synthase Type II
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- RNA, Messenger
- Rats
- Rats, Sprague-Dawley
- Sodium, Dietary