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Article

Vascular smooth muscle nitric oxide synthase anomalies in Dahl/Rapp salt-sensitive rats.

Hypertension (Dallas, Tex. : 1979) - 1 Apr 1998

Chen P Y, Gladish R D, Sanders P W

Abstract excerpt

Salt-sensitive hypertension in the Dahl/Rapp rat (S strain) is prevented by L-arginine. Based on the observations that dexamethasone prevented the antihypertensive effect of L-arginine in these animals and the suggestion that a locus in or near an inducible nitric oxide synthase (NOS) gene on chromosome 10 cosegregated with hypertension in some F2 crosses that utilized the S rat, the present study explored the...

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Identifiers

PMID: 9535415
DOI: 10.1161/01.hyp.31.4.918

Genes

NOS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Vascular smooth muscle nitric oxide synthase anomalies in Dahl/Rapp salt-sensitive rats.PMID 9535415Read ↗

Nitric oxide synthase (NOS2) mutation in Dahl/Rapp rats decreases enzyme stability.Semantic proximity Read ↗

Locus for the inducible, but not a constitutive, nitric oxide synthase cosegregates with blood pressure in the Dahl salt-sensitive rat.Semantic proximity Read ↗

Androgen-receptor defect abolishes sex differences in nitric oxide and reactivity to vasopressin in rat aorta.Semantic proximity Read ↗

The distorted alpha 2-adrenoceptor genotype distribution in F2 populations of Dahl salt sensitive and resistant rats cross.Semantic proximity Read ↗

Reduction in aortic smooth muscle beta-adrenergic responsiveness results in enhanced norepinephrine responsiveness in the Dahl salt-sensitive rat.Semantic proximity Read ↗

The Dahl salt-sensitive rat is a spontaneous model of superimposed preeclampsia.Semantic proximity Read ↗

Candidate genes for hypertension: insights from the Dahl S rat.Semantic proximity Read ↗

Antenatal Dexamethasone Exposure Impairs the High-Conductance Ca 2+ -Activated K + Channels via Epigenetic Alteration at Gene Promoter in Male OffspringSemantic proximity Read ↗

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