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The Genetic Basis of Graves Disease

14 Nov 2011

Abstract excerpt

The presented comprehensive review of current knowledge about genetic factors predisposing to Graves' disease (GD) put emphasis on functional significance of observed associations. In particular, we discuss recent efforts aimed at refining diseases associations found within the HLA complex and implicating HLA class I as well as HLA-DPB1 loci. We summarize data regarding non-HLA genes such as PTPN22, CTLA4, CD40,...

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PMID: 22654555
DOI: 10.2174/138920211798120772

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