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Article

Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning.

Journal of cell science - 15 Jan 2010

Lam Connie, Vergnolle Maïlys A S, Thorpe Lisa, Woodman Philip G, Allan Victoria J

Abstract excerpt

LIS1, NDE1 and NDEL1 modulate cytoplasmic dynein function in several cellular contexts. However, evidence that they regulate dynein-dependent organelle positioning is limited. Here, we show that depletion of NDE1 or NDEL1 alone profoundly affected the organisation of the Golgi complex but did not cause it to disperse, and slightly affected the position of endocytic compartments. However, striking dispersal of...

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Source

Identifiers

PMID: 20048338
DOI: 10.1242/jcs.059337

Genes

NDE1
NDEL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning.PMID 20048338Read ↗

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