Article
Functional characteristics of the Staphylococcus aureus δ-toxin allelic variant G10S.
Scientific reports - 10 Dec 2015
Cheung Gordon Y C, Yeh Anthony J, Kretschmer Dorothee, Duong Anthony C, Tuffuor Kwame, Fu Chih-Lung, Joo Hwang-Soo, Diep Binh A, Li Min, Nakamura Yuumi, Nunez Gabriel, Peschel Andreas, Otto Michael
Abstract excerpt
Staphylococcus aureus δ-toxin is a member of the phenol-soluble modulin (PSM) peptide family. PSMs have multiple functions in staphylococcal pathogenesis; for example, they lyse red and white blood cells and trigger inflammatory responses. Compared to other PSMs, δ-toxin is usually more strongly expressed but has only moderate cytolytic capacities. The amino acid sequences of S. aureus PSMs are well conserved...
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