Article
Cellular interactions of covR/S mutant group A Streptococci.
Microbes and infection - 1 Jan 2000
Langshaw Emma L, Pandey Manisha, Good Michael F
Abstract excerpt
Group A Streptococci (GAS) are responsible for a wide array of non-invasive and invasive diseases and varying immune sequelae with high rates of mortality and morbidity. GAS strains with a mutation in their covR/S regulatory system are hypervirulent with an increased capacity for causing invasive disease. covR/S mutants augment their virulence through the up-regulation of important virulence factors and target...
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