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Article

Functional roles of human kallikrein-related peptidases.

The Journal of biological chemistry - 27 Nov 2009

Sotiropoulou Georgia, Pampalakis Georgios, Diamandis Eleftherios P

Abstract excerpt

Kallikrein-related peptidases constitute a single family of 15 (chymo)trypsin-like proteases (KLK1-15) with pleiotropic physiological roles. Aberrant regulation of KLKs has been associated with diverse diseases such as hypertension, renal dysfunction, skin disorders, inflammation, neurodegeneration, and cancer. Recent studies suggested that coordinated activation and regulation of KLK activity are achieved via a...

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Source

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Identifiers

PMID: 19819870
DOI: 10.1074/jbc.R109.027946
PMCID: PMC2785139

Genes

KLK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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