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Article

The number of kringle IV repeats 3-10 is invariable in the human apo(a) gene.

Gene - 27 Feb 1998

Haibach C, Kraft H G, Köchl S, Abe A, Utermann G

Abstract excerpt

The human apolipoprotein(a) (apo(a)) gene is a member of a family of related genes including plasminogen, apo(a)rg-B and apo(a)rg-C, which are clustered on chromosome 6q 2,7. Apo(a) contains ten different types of plasminogen-like kringle IV repeats (K-IV 1-10) one of which (K-IV 2) varies in number resulting in a remarkable size polymorphism of the protein. Sequence analysis of human apo(a) alleles and indirect...

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PMID: 9524278
DOI: 10.1016/s0378-1119(97)00657-4

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