Article
Molecular definition of the extreme size polymorphism in apolipoprotein(a).
Human molecular genetics - 1 Jul 1993
Lackner C, Cohen J C, Hobbs H H
Abstract excerpt
Lipoprotein(a) [Lp(a)], an atherogenic lipoprotein, consists of an LDL particle complexed with a large glycoprotein, apolipoprotein(a) [apo(a)]. Apo(a) is one of the most polymorphic expressed sequences in the human genome. The glycoprotein varies in size over a approximately 500 kDa range due to length polymorphisms in the apo(a) gene. The region of the apo(a) gene responsible for this size polymorphism was...
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