Article
A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A.
Development (Cambridge, England) - 1 May 1998
Chen Y, Riese M J, Killinger M A, Hoffmann F M
Abstract excerpt
decapentaplegic (dpp) is a Transforming Growth Factor beta (TGF-beta)-related growth factor that controls multiple developmental processes in Drosophila. To identify components involved in dpp signaling, we carried out a genetic screen for dominant enhancer mutations of a hypomorphic allele of th...
Topics
- Activin Receptors
- Animals
- Bone Morphogenetic Protein 7
- Bone Morphogenetic Proteins
- DNA Mutational Analysis
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Genetic Complementation Test
- Insect Proteins
- Mesoderm
- Mutation
- Phenotype
- Protein Serine-Threonine Kinases