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Article

TGF-beta/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing.

Development (Cambridge, England) - 1 Jul 1998

Khalsa O, Yoon J W, Torres-Schumann S, Wharton K A

Abstract excerpt

Within a developing organism, cells receive many signals which control their proliferation, fate specification and differentiation. One group of such proteins is the TGF-beta/BMP class of related signaling molecules. Based on expression studies, multiple members of this class of ligands must impinge upon the same cells of a developing tissue; however, the role that multiple TGF-beta/BMP ligands may play in...

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PMID: 9636086
DOI: 10.1242/dev.125.14.2723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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TGF-beta/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing.PMID 9636086Read ↗

Genetic analysis of the bone morphogenetic protein-related gene, gbb, identifies multiple requirements during Drosophila development.Semantic proximity Read ↗

Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins.Semantic proximity Read ↗

A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A.Semantic proximity Read ↗

Dpp and Gbb exhibit different effective ranges in the establishment of the BMP activity gradient critical for Drosophila wing patterning.Semantic proximity Read ↗

Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc.Semantic proximity Read ↗

Context-dependent relationships between the BMPs gbb and dpp during development of the Drosophila wing imaginal disk.Semantic proximity Read ↗

Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila.Semantic proximity Read ↗

The interaction between two TGF-beta type I receptors plays important roles in ligand binding, SMAD activation, and gradient formation.Semantic proximity Read ↗

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