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Article

Molecular lesions associated with alleles of decapentaplegic identify residues necessary for TGF-beta/BMP cell signaling in Drosophila melanogaster.

Genetics - 1 Feb 1996

Wharton K, Ray R P, Findley S D, Duncan H E, Gelbart W M

Abstract excerpt

We have identified the molecular lesions associated with six point mutations in the Drosophila TGF-beta homologue decapentaplegic (dpp). The sites of these mutations define residues within both the pro and ligand regions that are essential for dpp function in vivo. While all of these mutations affect residues that are highly conserved among TGF-beta superfamily members, the phenotypic consequences of the...

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Identifiers

PMID: 8852848
DOI: 10.1093/genetics/142.2.493
PMCID: PMC1206983

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Molecular lesions associated with alleles of decapentaplegic identify residues necessary for TGF-beta/BMP cell signaling in Drosophila melanogaster.PMID 8852848Read ↗

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