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Article

Molecular organization of the decapentaplegic gene in Drosophila melanogaster.

Genes & development - 1 Jul 1990

St Johnston R D, Hoffmann F M, Blackman R K, Segal D, Grimaila R, Padgett R W, Irick H A, Gelbart W M

Abstract excerpt

The decapentaplegic (dpp) locus of Drosophila melanogaster is a greater than 55 kb genetic unit required for proper pattern formation during the embryonic and imaginal development of the organism. We have proposed that these morphogenetic functions result from the action of a secreted transforming growth factor-beta (TGF-beta)-related protein product encoded by dpp. In this paper we localize 60 mutations on the...

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PMID: 2120113
DOI: 10.1101/gad.4.7.1114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Molecular organization of the decapentaplegic gene in Drosophila melanogaster.PMID 2120113Read ↗

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-beta family.Semantic proximity Read ↗

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.Semantic proximity Read ↗

Identification of chromosomal regions involved in decapentaplegic function in Drosophila.Semantic proximity Read ↗

Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements.Semantic proximity Read ↗

A screen for modifiers of decapentaplegic mutant phenotypes identifies lilliputian, the only member of the Fragile-X/Burkitt's Lymphoma family of transcription factors in Drosophila melanogaster.Semantic proximity Read ↗

Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila.Semantic proximity Read ↗

Molecular lesions associated with alleles of decapentaplegic identify residues necessary for TGF-beta/BMP cell signaling in Drosophila melanogaster.Semantic proximity Read ↗

Embryonic expression patterns of the Drosophila decapentaplegic gene: separate regulatory elements control blastoderm expression and lateral ectodermal expression.Semantic proximity Read ↗

Analysis of the shortvein cis-regulatory region of the decapentaplegic gene of Drosophila melanogaster.Semantic proximity Read ↗

A novel splice variant of the decapentaplegic (dpp) gene in the wild silkworm, Bombyx mandarina.Semantic proximity Read ↗

Identification of two regions from the Drosophila decapentaplegic gene required for embryonic midgut development and larval viability.Semantic proximity Read ↗

A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A.Semantic proximity Read ↗

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