The origins of polypeptide domains.

Abstract excerpt

Three decades ago Gilbert posited that novel proteins arise by re-shuffling genomic sequences encoding polypeptide domains. Today, with numerous genomes and countless genes sequenced, it is well established that recombination of sequences encoding polypeptide domains plays a major role in protein evolution. There is, however, less evidence to suggest how the novel polypeptide domains, themselves, arise. Recent...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Evolution, Molecular
• Share to Exons
• Share to Gene Duplication