Article
Proliferation-dependent replication in primary macrophages of macrophage-tropic HIV type 1 variants.
AIDS research and human retroviruses - 1 Mar 1998
Kootstra N A, Schuitemaker H
Abstract excerpt
We previously demonstrated that completion of reverse transcription in macrophages inoculated with the HIV-1 Ba-L variant was established only in the subpopulation of cells with proliferative capacity. In our present study we further extended this observation with three additional HIV-1 isolates,...
Topics
- Acquired Immunodeficiency Syndrome
- Base Sequence
- Bromodeoxyuridine
- Cell Division
- Cells, Cultured
- DNA Primers
- Genetic Variation
- HIV-1
- Humans
- Kinetics
- Macrophages
- Polymerase Chain Reaction
- Transcription, Genetic
- Virus Replication