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Article

Structural model of the complete poly(A) region of HIV-1 pre-mRNA.

Journal of biomolecular structure & dynamics - 1 Oct 2013

Zarudnaya Margarita I, Potyahaylo Andriy L, Kolomiets Iryna M, Hovorun Dmytro М

Abstract excerpt

In the HIV-1 retrovirus, identical sequences encompassing the AAUAAA hexamer and the U/GU-rich downstream sequence element (DSE) that compose the core poly(A) site are present at both the 5' and 3' ends of the HIV-1 pre-mRNA. The AAUAAA hexamer is partly occluded by base pairing in the upper part of a semi-stable polyA hairpin. This sets the stage for regulation of HIV-1 polyadenylation, which involves reaction...

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Identifiers

PMID: 22963228
DOI: 10.1080/07391102.2012.718530

Genes

DSE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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