Article
Genetic characterization of antithrombin, protein C, and protein S deficiencies in Polish patients.
Polish archives of internal medicine - 9 Aug 2017
Wypasek Ewa, Corral Javier, Alhenc-Gelas Martine, Sydor Wojciech, Iwaniec Teresa, Celińska-Lowenhoff Magdalena, Potaczek Daniel P, Blecharczyk Aleksandra, Zawilska Krystyna, Musiał Jacek, Undas Anetta
Abstract excerpt
INTRODUCTION Inherited deficiencies of natural anticoagulants such as antithrombin (AT; gene: SERPINC1), protein C (PC; PROC), and protein S (PS; PROS1), with the prevalence in the general European population of 0.02% to 0.17%, 0.2% to 0.3%, and 0.5%, respectively, are associated with increased risk of thromboembolic events. Only a few case reports of Polish deficient patients with known causal mutations have...
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