Article
HLA class II DRB1, DQB1 and DPB1 genotypic associations with peanut allergy: evidence from a family-based and case-control study.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Feb 1998
Howell W M, Turner S J, Hourihane J O, Dean T P, Warner J O
Abstract excerpt
BACKGROUND: Peanut is one of the most common foods provoking allergic reactions and is the most frequent cause of fatal and near-fatal food-induced anaphylaxis. However, as yet, little is known of the genetic and immunological mechanisms which underly peanut allergy. OBJECTIVE: Based on findings...
Topics
- Arachis
- Case-Control Studies
- DNA
- Family Health
- Food Hypersensitivity
- Gene Frequency
- Genes, MHC Class II
- Genetic Markers
- Genotype
- HLA-DP Antigens
- HLA-DP beta-Chains
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Histocompatibility Antigens Class II
- Humans