Article
Difference in chromatin packaging between active and inactive X chromosomes by fractionation and allele-specific detection.
Biochemical and biophysical research communications - 6 Mar 1998
Endo Y, Watanabe T, Kuwabara K, Tsunashima K, Mishima Y, Arakawa M, Takagi N, Kominami R
Abstract excerpt
Using a novel method consisting of chromatin fractionation and allele-specific detection, chromatin packaging is compared between active X (Xa) and inactive X (Xi) chromosomes for five tumor cell clones that were derived from inter-subspecific F1 female mice. Separation of heterochromatic (H) and euchromatic (E) fractions is monitored by hybridization with subtelomeric satellite DNA and ribosomal RNA gene and by...
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