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Article

Spatial and structural segregation of the transcribed and nontranscribed alleles of c-myc in Namalva-S cells.

Oncology research - 1 Jan 1994

Djondjurov L P, Andreeva M M, Markova D Z, Donev R M

Abstract excerpt

By using various approaches we received evidence that, in Namalva-S cells carrying a t(8;14) translocation and highly expressing c-myc, the two alleles of the gene are spatially and structurally segregated. Spatial segregation of the alleles was observed in all nuclei analyzed by in situ hybridization technique. Their structural segregation, i.e., association with different intranuclear structures, was confirmed...

Topics

Alleles
Animals
Base Sequence
Burkitt Lymphoma
Cell Fractionation
Chromatin
Chromosome Mapping
DNA Probes
Genes, Neoplasm
Genes, myc
Globins
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

In Situ Hybridization

Mice

RNA

Transcription, Genetic

Tumor Cells, Cultured

Source

Identifiers

PMID: 7534509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7534509-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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