Article
Association between the GABA(A) receptor alpha5 subunit gene locus (GABRA5) and bipolar affective disorder.
American journal of medical genetics - 7 Feb 1998
Papadimitriou G N, Dikeos D G, Karadima G, Avramopoulos D, Daskalopoulou E G, Vassilopoulos D, Stefanis C N
Abstract excerpt
Genetic factors seem to play an important role in the pathogenesis of affective disorder. The candidate gene strategies are being used, among others, to identify the genes conferring vulnerability to the disease. The genes coding for the receptors of gamma-aminobutyric acid (GABA) have been proposed as candidates for affective disorder, since the GABA neurotransmitter system has been implicated in the...
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