Article
Multimarkerhaplotypes within the serotonin transporter gene suggest evidence of an association with bipolar disorder.
American journal of medical genetics - 4 Dec 2000
Mynett-Johnson L, Kealey C, Claffey E, Curtis D, Bouchier-Hayes L, Powell C, McKeon P
Abstract excerpt
Previously we obtained modest linkage evidence implicating 17q11. 1-12 in bipolar disorder. A modified genome screen, based on gene-rich regions, on a collection of Irish sib-pair nuclear families revealed excess allele sharing at markers flanking the gene encoding the serotonin transporter (5-HTT; hSERT). Here we describe a study designed to combine the advantages of family-based association studies with the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.