Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic mutations that contribute to breast cancer.

Biochemical Society symposium - 1 Jan 1998

Callahan R

Abstract excerpt

Cytogenetic and molecular analyses of primary sporadic human breast carcinomas have documented at least 12 different chromosome arms affected by loss of heterozygosity (LOH). This has been taken as evidence for the presence of putative tumour suppressor genes in the remaining allele within the affected regions. We have previously identified three regions on chromosome 17q that are affected by LOH in primary human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Chromosomes, Human, Pair 17
Share to Loss of Heterozygosity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mammary Neoplasms, Experimental

Share to Mutation

Share to Proto-Oncogene Proteins

Share to Receptors, Cell Surface

Source

Identifiers

PMID: 9513725

Genes

NOTCH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic mutations that contribute to breast cancer.PMID 9513725Read ↗

Mutations in breast cancer.Semantic proximity Read ↗

Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer.Semantic proximity Read ↗

Genetic alterations in breast cancer.Semantic proximity Read ↗

Somatic mutations in leukocytes infiltrating primary breast cancersSemantic proximity Read ↗

Loss, mutation and deregulation of L3MBTL4 in breast cancers.Semantic proximity Read ↗

Genes affected by mouse mammary tumor virus (MMTV) proviral insertions in mouse mammary tumors are deregulated or mutated in primary human mammary tumors.Semantic proximity Read ↗

Somatic mutations and human breast cancer. A status report.Semantic proximity Read ↗

Somatic genetic changes in human breast cancer.Semantic proximity Read ↗

Detailed deletion analysis of sporadic breast tumors defines an interstitial region of allelic loss on 17q25.Semantic proximity Read ↗

Mutations in human breast cancer cells: dominantly-acting oncogenes and tumor suppressor genes suggest strategies for targeted interference.Semantic proximity Read ↗

Accumulation of genetic alterations and progression of primary breast cancer.Semantic proximity Read ↗

Allelic loss mapping and physical delineation of a region harboring a thymic lymphoma suppressor gene on mouse chromosome 16.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.