Somatic mutations that contribute to breast cancer.

Article

Somatic mutations that contribute to breast cancer.

Biochemical Society symposium - 1 Jan 1998

Callahan R

Abstract excerpt

Cytogenetic and molecular analyses of primary sporadic human breast carcinomas have documented at least 12 different chromosome arms affected by loss of heterozygosity (LOH). This has been taken as evidence for the presence of putative tumour suppressor genes in the remaining allele within the af...

Topics

Animals
Breast Neoplasms
Chromosomes, Human, Pair 17
Female
Humans
Loss of Heterozygosity
Mammary Neoplasms, Experimental
Mammary Tumor Virus, Mouse
Mice
Mutation
Proto-Oncogene Proteins
Receptor, Notch4
Receptors, Cell Surface
Receptors, Notch

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