Somatic genetic changes in human breast cancer.

doi:10.1016/0304-419x(94)90009-4

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Article

Somatic genetic changes in human breast cancer.

Biochimica et biophysica acta - 30 Dec 1994

Devilee P, Cornelisse C J

Abstract excerpt

Quantitative imbalance in chromosomal material relative to the normal diploid situation is the most conspicuous genetic change in breast tumors, affecting virtually all chromosomes in varying frequencies. This imbalance is reflected by deviant DNA stemlines observed in DNA flow cytometry analysis...

Topics

Breast Neoplasms
Cytogenetics
DNA Replication
Flow Cytometry
Genes, Tumor Suppressor
Genotype
Humans
In Situ Hybridization

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