Article
Mutations in breast cancer.
Cancer letters - 23 Mar 1995
Cropp C S
Abstract excerpt
The genetics of spontaneous breast cancer is reviewed. We have identified three regions of amplification and nine chromosomal arms with deletions in the genome. The significance and interrelations of these mutations is discussed with respect to the complex genetics of breast carcinoma. Recent work identifying a commonly deleted region between D17S846 and D17S746 is presented, which is approximately 0.5-1.0 Mb...
Topics
- Breast Neoplasms
- DNA, Neoplasm
- Humans
- Mutation