Article
CD14- mononuclear stromal cells support (CD14+) monocyte-osteoclast differentiation in aneurysmal bone cyst.
Laboratory investigation; a journal of technical methods and pathology - 1 Apr 2012
Taylor Richard Mi, Kashima Takeshi G, Hemingway Francesca K E, Dongre Arundhati, Knowles Helen J, Athanasou Nicholas A
Abstract excerpt
Aneurysmal bone cyst (ABC) is a benign osteolytic bone lesion in which there are blood-filled spaces separated by fibrous septa containing giant cells. The nature of the giant cells in this lesion and the mechanism of bone destruction in ABC is not certain. In this study, we have analysed several characteristics of mononuclear and multinucleated cells in the ABC and examined the cellular and molecular mechanisms...
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