Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition.

Genes & development - 15 Mar 1998

Berglund J A, Abovich N, Rosbash M

Abstract excerpt

During the early events of pre-mRNA splicing, intronic cis-acting sequences are recognized and interact through a network of RNA-RNA, RNA-protein, and protein-protein contacts. Recently, we identified a branchpoint sequence binding protein in yeast (BBP). The mammalian ortholog (mBBP/SF1) also binds specifically to branchpoint sequences and interacts with the well studied mammalian splicing factor U2AF65, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Protein Binding
Share to Binding Sites
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Nuclear Proteins

Share to RNA-Binding Proteins

Share to RNA Splicing

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 9512519
DOI: 10.1101/gad.12.6.858
PMCID: PMC316625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition.PMID 9512519Read ↗

Recognition of RNA Branch Point Sequences by the KH Domain of Splicing Factor 1 (Mammalian Branch Point Binding Protein) in a Splicing Factor ComplexSemantic proximity Read ↗

The human branchpoint-interacting stem loop sequence and structure regulates U2 snRNA expression, branchpoint recognition, and transcriptomeSemantic proximity Read ↗

Functional analysis of Hsh155/SF3b1 interactions with the U2 snRNA/branch site duplex.Semantic proximity Read ↗

The human branchpoint-interacting stem-loop sequence and structure regulates U2 snRNA expression, branchpoint recognition, and the transcriptome.Semantic proximity Read ↗

Structural basis for recognition of the intron branch site RNA by splicing factor 1.Semantic proximity Read ↗

A novel function for the U2AF 65 splicing factor in promoting pre-mRNA 3'-end processing.Semantic proximity Read ↗

Accumulation of a novel spliceosomal complex on pre-mRNAs containing branch site mutations.Semantic proximity Read ↗

Structure of PTB bound to RNA: specific binding and implications for splicing regulation.Semantic proximity Read ↗

RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans.Semantic proximity Read ↗

Structure-function analysis and genetic interactions of the yeast branchpoint binding protein Msl5.Semantic proximity Read ↗

Cancer-associated mutations in SF3B1 disrupt the interaction between SF3B1 and DDX42.Semantic proximity Read ↗

Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.