Article
Allelic diversity at the primate MHC-DMB locus: presence of a conserved tyrosine inhibitory motif in the cytoplasmic tail.
Tissue antigens - 1 Feb 1998
Alvarez M, Recio M J, Martinez-Laso J, Pérez-Blas M, Garcia-de-la-Torre C, Vargas-Alarcón G, Alegre R, Gomez-Casado E, Arnaiz-Villena A
Abstract excerpt
Ten new primate Mhc-DMB complete cDNA sequences have been obtained in chimpanzee (n=four), gorilla (n=three) and orangutan (n=three); this gene has not been previously studied in these species. Exonic allelism has been recorded all along the molecule domains and also in the leader peptide, but not in the transmembrane segment. An analysis of the residues critical in the conformation of the Mhc-DR peptide-binding...
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