Article
Frameshifts, base substitutions and minute deletions constitute X-ray-induced mutations in the endogenous tonB gene of Escherichia coli K12.
Mutation research - 1 Dec 1997
Kanbashi K, Wang X, Komura J, Ono T, Yamamoto K
Abstract excerpt
We have analyzed the DNA sequence changes in a total of 127 X-ray-induced mutations in the endogenous tonB gene of Escherichia coli cells. Frameshifts accounted for 61 mutations among which 51 were a - 1 frameshift. The second most commonly found mutations were base substitutions (20 transversion...
Topics
- Bacterial Proteins
- Chromosome Mapping
- Coliphages
- DNA Damage
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Frameshift Mutation
- Gamma Rays
- Membrane Proteins
- Mutation
- Plasmids
- Point Mutation
- Repetitive Sequences, Nucleic Acid
- Sequence Analysis, DNA
- Sequence Deletion
- Transfection
