Article
Use of data from bacteria to interpret data on DNA damage processing in mammalian cells.
Mutation research - 1 Jan 2000
Hutchinson F
Abstract excerpt
The most important reason for determining the changes in base sequence in the processing of DNA damage is to determine mechanisms. Currently, much more is known about these mechanisms in prokaryotes, partly because the experiments are easier and quicker to do in bacteria, and partly because of the wealth of well characterized bacterial mutants deficient in various DNA repair pathways. This paper summarizes some...
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