Article
Adult rat ventricular myocytes cultured in defined medium: phenotype and electromechanical function.
The American journal of physiology - 1 Aug 1993
Ellingsen O, Davidoff A J, Prasad S K, Berger H J, Springhorn J P, Marsh J D, Kelly R A, Smith T W
Abstract excerpt
We studied primary short-term cultures of adult rat ventricular myocytes in defined medium to determine whether phenotype and electromechanical function are maintained in rod-shaped, quiescent cells. Although > 80% of the myocytes retained their rod-shaped in vivo morphology for up to 72 h, contr...
Topics
- Animals
- Calcium
- Cell Survival
- Cells, Cultured
- Culture Media
- Electrophysiology
- Gene Expression
- Heart
- Heart Ventricles
- Myocardial Contraction
- Myocardium
- Phenotype
