Article
Chondrogenic phenotype of perichondrium-derived chondroprogenitor cells is influenced by transforming growth factor-beta 1.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Nov 1997
Dounchis J S, Goomer R S, Harwood F L, Khatod M, Coutts R D, Amiel D
Abstract excerpt
Our laboratory has developed a method for the repair of osteochondral defects by implanting cultured perichondrial cells attached to a biodegradable polylactic acid scaffold. The success of this approach depends in part on the proliferative characteristics and the phenotype of the implanted cells. Transforming growth factor-beta 1 has been reported to influence these parameters in several mesenchymal-derived...
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