Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type-II collagen gene expression is transiently upregulated in experimentally induced degeneration of rabbit intervertebral disc.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jul 1997

Takaishi H, Nemoto O, Shiota M, Kikuchi T, Yamada H, Yamagishi M, Yabe Y

Abstract excerpt

To clarify phenotypic alterations of intervertebral disc cells during the repair process, we cloned partial type-II collagen cDNA from rabbits and analyzed the level of expression of type-II collagen mRNA in disc degeneration. An animal model was created by surgical denucleation of rabbit intervertebral discs through an extraperitoneal approach. Eight animals each from an experimental and a control group were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Collagen

Share to DNA, Complementary

Share to Gene Expression

Share to In Situ Hybridization

Share to Phenotype

Share to RNA, Messenger

Source

Identifiers

PMID: 9379262
DOI: 10.1002/jor.1100150408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type-II collagen gene expression is transiently upregulated in experimentally induced degeneration of rabbit intervertebral disc.PMID 9379262Read ↗

Comparative Gene Expression Profiling of Normal and Degenerative DiscsSemantic proximity Read ↗

1999 Volvo Award Winner in Basic Science StudiesSemantic proximity Read ↗

Phenotypic characteristics of rabbit intervertebral disc cells. Comparison with cartilage cells from the same animals.Semantic proximity Read ↗

Changes in gene expression and protein distribution at different stages of mechanically induced disc degeneration—an in vivo study on the New Zealand white rabbitSemantic proximity Read ↗

A Fibronectin Fragment Stimulates Intervertebral Disc Degeneration In VivoSemantic proximity Read ↗

Gene Therapy Approaches for Intervertebral Disc DegenerationSemantic proximity Read ↗

Gene expression of type II collagens in chondro-osteophytes in experimental osteoarthritisSemantic proximity Read ↗

Induction of Intervertebral Disc–Like Cells From Adult Mesenchymal Stem CellsSemantic proximity Read ↗

[Expression and significance of Wnt/β-catenin signaling pathway in vitro natural degenerationmodel of endplate chondrocytes in rats].Semantic proximity Read ↗

Nonviral Transfection With Brachyury Reprograms Human Intervertebral Disc Cells to a Pro‐Anabolic Anti‐Catabolic/Inflammatory Phenotype: A Proof of Concept StudySemantic proximity Read ↗

Differential Phenotype of Intervertebral Disc CellsSemantic proximity Read ↗

Chondrogenic phenotype of perichondrium-derived chondroprogenitor cells is influenced by transforming growth factor-beta 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.