Article
NF-kappaB mediated transcriptional activation is enhanced by the architectural factor HMGI-C.
Nucleic acids research - 15 Mar 1998
Mantovani F, Covaceuszach S, Rustighi A, Sgarra R, Heath C, Goodwin G H, Manfioletti G
Abstract excerpt
High mobility group I proteins (HMGI, HMGY and HMGI-C) are a family of low molecular mass non-histone nuclear proteins which constitute an important component of the active chromatin structure. Two members of this family, HMGI and HMGY, have been demonstrated to contribute to the transcriptional regulation of several promoters by interacting with the DNA and with different transcription factors. On the contrary,...
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