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Article

Functional idiosyncrasies of tRNA isoacceptors in cognate and noncognate aminoacylation systems.

Biochimie - 1 Jan 2004

Fender Aurélie, Sissler Marie, Florentz Catherine, Giegé Richard

Abstract excerpt

The specificity of transfer RNA aminoacylation by cognate aminoacyl-tRNA synthetase is a crucial step for synthesis of functional proteins. It is established that the aminoacylation identity of a single tRNA or of a family of tRNA isoacceptors is linked to the presence of positive signals (determinants) allowing recognition by cognate synthetases and negative signals (antideterminants) leading to rejection by the...

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Identifiers

PMID: 14987797
DOI: 10.1016/j.biochi.2003.11.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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