Expression and characterization of a dopamine D4R variant associated with delusional disorder.

doi:10.1016/s0014-5793(97)01617-7

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Article

Expression and characterization of a dopamine D4R variant associated with delusional disorder.

FEBS letters - 30 Jan 1998

Zenner M T, Nobile M, Henningsen R, Smeraldi E, Civelli O, Hartman D S, Catalano M

Abstract excerpt

Multiple genetic polymorphisms of the human dopamine D4 receptor (hD4R) have been identified including a 12 bp repeat in exon 1 associated with a psychotic condition called delusional disorder. Competition binding assays revealed minor pharmacological differences between the recombinant A1 (norma...

Topics

Animals
Antipsychotic Agents
CHO Cells
Clozapine
Cricetinae
Dopamine
Dopamine Agonists
Dopamine Antagonists
Epinephrine
Genetic Variation
Guanosine 5'-O-(3-Thiotriphosphate)
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kinetics

Norepinephrine

Polymorphism, Genetic

Quinpirole

Receptors, Dopamine D2

Receptors, Dopamine D4

Source

Open in PubMed

Identifiers

PMID: 9489994
DOI: 10.1016/s0014-5793(97)01617-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9489994-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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