Article
Effect of DNA repair on aging of transgenic Drosophila melanogaster: I. mei-41 locus.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Sept 2003
Symphorien Sonia, Woodruff R C
Abstract excerpt
Aging appears to be increased by diminished DNA repair. To study this relationship between aging and DNA repair, we measured the life span of Drosophila melanogaster males in the absence of mei-41 excision repair and transgenic flies with 1 or 2 extra copies of the mei-41 wild-type gene. Life span was significantly reduced in the absence of repair and was significantly increased by an extra dose of excision...
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