Article
Apurinic endonuclease activity from wild-type and repair-deficient mei-9 Drosophila ovaries.
Molecular & general genetics : MGG - 1 May 1990
Venugopal S, Guzder S N, Deutsch W A
Abstract excerpt
An endonuclease which acts on apurinic (AP) sites in DNA was partially purified from Drosophila ovaries. The enzyme present in the female germ line has a molecular weight of 63,000 daltons, is Mg++ dependent, and produces a site upon cleaving depurinated DNA that supports DNA repair synthesis. Although the same characteristics are shared by the enzyme present in the excision-deficient mutant mei-9, specific...
Topics
- Animals
- DNA
- DNA Repair
- DNA-(Apurinic or Apyrimidinic Site) Lyase
- Deoxyribonuclease IV (Phage T4-Induced)
- Drosophila
- Endodeoxyribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Female
- Genes