Article
Evidence against linkage of familial combined hyperlipidemia to the apolipoprotein AI-CIII-AIV gene complex.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 1998
Wijsman E M, Brunzell J D, Jarvik G P, Austin M A, Motulsky A G, Deeb S S
Abstract excerpt
Familial combined hyperlipidemia (FCHL) was originally described as a disorder characterized by elevated levels of either plasma cholesterol or triglyceride (TG) or both in members ofthe same family. More recent studies have indicated that apolipoprotein B levels (apoB) are also elevated in these...
Topics
- Apolipoprotein A-I
- Apolipoprotein C-III
- Apolipoproteins A
- Apolipoproteins C
- DNA
- Female
- Genetic Linkage
- Humans
- Hyperlipidemias
- Lipids
- Lod Score
- Male
- Multigene Family
- Pedigree
- Phenotype
- Polymorphism, Genetic