Article
Association between genetic variation at the APO AI-CIII-AIV gene cluster and familial combined hyperlipidaemia.
Clinical genetics - 1 Dec 1994
Xu C F, Talmud P, Schuster H, Houlston R, Miller G, Humphries S
Abstract excerpt
By using chemical cleavage mismatch analysis and the single strand conformation polymorphism technique, DNA fragments of the apo CIII gene, including the 5' flanking region and all the exons, were screened for sequence changes underlying the observed association between familial combined hyperlip...
Topics
- Adult
- Aged
- Alleles
- Analysis of Variance
- Apolipoprotein A-I
- Apolipoprotein C-III
- Apolipoproteins A
- Apolipoproteins C
- Base Composition
- Case-Control Studies
- Chi-Square Distribution
- DNA Mutational Analysis