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Article

Two newly identified SNPs in the APO AI-CIII intergenic region are strongly associated with familial combined hyperlipidaemia.

European journal of clinical investigation - 1 Oct 2001

Groenendijk M, Cantor R M, Funke H, Dallinga-Thie G M

Abstract excerpt

BACKGROUND: We previously reported linkage and association of the apoAI-CIII-AIV gene region on chromosome 11 with familial combined hyperlipidaemia (FCHL). However, the observed epistasis resulting in an increased susceptibility to FCHL still remains unexplained. We hypothesize that the region between the apo AI and apo CIII genes may harbour functional mutations that might be in linkage disequilibrium with the...

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Share to Apolipoprotein A-I
Share to Apolipoprotein C-III

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to DNA, Intergenic

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Share to Hyperlipidemia, Familial Combined

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Source

Identifiers

PMID: 11737222
DOI: 10.1046/j.1365-2362.2001.00888.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Two newly identified SNPs in the APO AI-CIII intergenic region are strongly associated with familial combined hyperlipidaemia.PMID 11737222Read ↗

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Linkage disequilibrium of three polymorphic RFLP markers in the apolipoprotein AI-CIII gene cluster on chromosome 11.Semantic proximity Read ↗

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