Article
Aging, mating, and the evolution of mtDNA heteroplasmy in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America - 3 Mar 1998
Kann L M, Rosenblum E B, Rand D M
Abstract excerpt
Heteroplasmy, the presence of more than one type of mtDNA within cells, is common in animals and has been associated with aging and disease in humans. Changes in the frequencies of mtDNA variants between cell and animal generations thus bears on the evolution of mtDNA and the progression of diverse pathologies. We have used densitometry of Southern blots of individual heteroplasmic Drosophila melanogaster to...
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