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Article

Drosophila synaptotagmin I null mutants show severe alterations in vesicle populations but calcium-binding motif mutants do not.

The Journal of comparative neurology - 1 May 2006

Loewen Carin A, Royer Suzanne M, Reist Noreen E

Abstract excerpt

Synaptotagmin I is a synaptic vesicle protein postulated to mediate vesicle docking, vesicle recycling, and the Ca(2+) sensing required to trigger vesicle fusion. Analysis of synaptotagmin I knockouts (sytI(NULL) mutants) in both Drosophila and mice led to these hypotheses. Although much research on the mechanisms of synaptic transmission in Drosophila is performed at the third instar neuromuscular junction, the...

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Identifiers

PMID: 16528727
DOI: 10.1002/cne.20868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Drosophila synaptotagmin I null mutants show severe alterations in vesicle populations but calcium-binding motif mutants do not.PMID 16528727Read ↗

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Transmembrane tethering of synaptotagmin to synaptic vesicles controls multiple modes of neurotransmitter release.Semantic proximity Read ↗

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