Article
New hepatitis B virus mutant form in a blood donor that is undetectable in several hepatitis B surface antigen screening assays.
Transfusion - 1 Jan 1998
Jongerius J M, Wester M, Cuypers H T, van Oostendorp W R, Lelie P N, van der Poel C L, van Leeuwen E F
Abstract excerpt
BACKGROUND: Envelope mutant forms of hepatitis B virus (HBV), impairing HBV antibody recognition, have been reported with mutations in single or multiple sites of the hepatitis B surface antigen (HBsAg) group-specific "a" determinant. Blood donors infected with such an HBsAg mutant form of HBV may escape detection by HBsAg screening assays and therefore may affect the safety of the blood supply. CASE REPORT: A...
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