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Article

Detecting hepatitis B surface antigen mutants.

Emerging infectious diseases - 1 Feb 2006

Coleman Paul F

Abstract excerpt

Hepatitis B viral mutants can emerge in patients as a result of selection pressure from either immune response or treatment options. Mutations that occur within the immunodominant epitopes of hepatitis B surface antigen (HBsAg) allow mutant virus to propagate in the presence of a neutralizing immune response, while wild-type virus is reduced to undetectable levels. HBsAg mutants present as false-negative results...

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Identifiers

PMID: 16494742
DOI: 10.3201/eid1203.050038
PMCID: PMC3293431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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