Article
Surveillance for hepatitis B surface antigen mutants.
Journal of medical virology - 1 Jan 2006
Coleman Paul F
Abstract excerpt
Hepatitis B viral (HBV) mutants can emerge in patients as a result of selection pressure from treatment options. Some mutations that occur in the immunodominant "a" determinant of hepatitis B surface antigen (HBsAg) can present as false negative results in HBsAg immunoassays. The mutation position in HBsAg and the type of mutation impacts immunoassay performance. HBsAg mutants will continue to emerge in response...
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