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Article

Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1.

Science (New York, N.Y.) - 27 Feb 1998

Gale C A, Bendel C M, McClellan M, Hauser M, Becker J M, Berman J, Hostetter M K

Abstract excerpt

Adhesion and the ability to form filaments are thought to contribute to the pathogenicity of Candida albicans, the leading cause of fungal disease in immunocompromised patients. Int1p is a C. albicans surface protein with limited similarity to vertebrate integrins. INT1 expression in Saccharomyces cerevisiae was sufficient to direct the adhesion of this normally nonadherent yeast to human epithelial cells....

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Identifiers

PMID: 9478896
DOI: 10.1126/science.279.5355.1355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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