Article
Calmodulin binding to Dfi1p promotes invasiveness of Candida albicans.
PloS one - 1 Jan 2013
Davis Talya R, Zucchi Paola C, Kumamoto Carol A
Abstract excerpt
Candida albicans, a dimorphic fungus, undergoes hyphal development in response to many different environmental cues, including growth in contact with a semi-solid matrix. C. albicans forms hyphae that invade agar when cells are embedded in or grown on the surface of agar, and the integral membrane protein Dfi1p is required for this activity. In addition, Dfi1p is required for full activation of mitogen activated...
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