Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Candida albicans INT1-induced filamentation in Saccharomyces cerevisiae depends on Sla2p.

Molecular and cellular biology - 1 Feb 2001

Asleson C M, Bensen E S, Gale C A, Melms A S, Kurischko C, Berman J

Abstract excerpt

The Candida albicans INT1 gene is important for hyphal morphogenesis, adherence, and virulence (C. Gale, C. Bendel, M. McClellan, M. Hauser, J. M. Becker, J. Berman, and M. Hostetter, Science 279:1355-1358, 1998). The ability to switch between yeast and hyphal morphologies is an important virulence factor in this fungal pathogen. When INT1 is expressed in Saccharomyces cerevisiae, cells grow with a filamentous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Candida albicans
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle Proteins

Share to Cytoskeletal Proteins

Share to Genes, Fungal

Share to Genetic Complementation Test

Share to Protein-Tyrosine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 11158313
DOI: 10.1128/MCB.21.4.1272-1284.2001
PMCID: PMC99580

Genes

SLA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Candida albicans INT1-induced filamentation in Saccharomyces cerevisiae depends on Sla2p.PMID 11158313Read ↗

Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1.Semantic proximity Read ↗

SLA2 mutations cause SWE1-mediated cell cycle phenotypes in Candida albicans and Saccharomyces cerevisiae.Semantic proximity Read ↗

Candida albicans septin mutants are defective for invasive growth and virulence.Semantic proximity Read ↗

Sla1p is a functionally modular component of the yeast cortical actin cytoskeleton required for correct localization of both Rho1p-GTPase and Sla2p, a protein with talin homology.Semantic proximity Read ↗

The role of Candida albicans SPT20 in filamentation, biofilm formation and pathogenesis.Semantic proximity Read ↗

Spt3 Plays Opposite Roles in Filamentous Growth in Saccharomyces cerevisiae and Candida albicans and Is Required for C. albicans VirulenceSemantic proximity Read ↗

Septin function in Candida albicans morphogenesis.Semantic proximity Read ↗

Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae.Semantic proximity Read ↗

An interaction between Sla1p and Sla2p plays a role in regulating actin dynamics and endocytosis in budding yeast.Semantic proximity Read ↗

MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation.Semantic proximity Read ↗

Polarized hyphal growth in Candida albicans requires the Wiskott-Aldrich Syndrome protein homolog Wal1p.Semantic proximity Read ↗

Strains isogenic to S288C used in the yeast genome sequencing programme carry a functional KSS1 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.